Journal: Parasites & Vectors
Article Title: Detoxification enzymes associated with insecticide resistance in laboratory strains of Anopheles arabiensis of different geographic origin
doi: 10.1186/1756-3305-5-113
Figure Lengend Snippet: The volcano plot of SENN-base and SENN-DDT microarray data. The plot represents both statistical relevance, in the form of the p -value on the y -axis, and biological relevance in the form of the fold change on the x -axis. The cut-offs for significance are shown (adj. p -value ≤ 0.05; FC ≥ 1.5) and those genes that meet the criteria are labeled. Note that all positive fold change (FC) values represent genes over-transcribed in the resistant colony (SENN-DDT), while negative FC values represent the genes over transcribed in the susceptible colony (SENN-base).
Article Snippet: The Pronto!™ Universal Microarray Hybridization Kit (Corning) was used, but a 1.5x preparation of each wash solution was used, along with slightly reduced exposure times, following a series of optimization experiments.
Techniques: Microarray, Labeling